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γ-L-Glutamyl-3-carboxy-4-nitroanilide, monoammonium salt CAS:63699-78-5

γ-L-Glutamyl-3-carboxy-4-nitroanilide, monoammonium salt is a chemical compound that is commonly used in biochemical research and related fields. It is a synthetic derivative of L-glutamate, an amino acid.

This compound is often utilized as a substrate for enzymes called γ-glutamyl transpeptidases, which play a role in various physiological processes. It is commonly used in enzymatic assays to study the activity and inhibition of these enzymes.

 

 


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Application and Effect

γ-L-Glutamyl-3-carboxy-4-nitroanilide, monoammonium salt is a substrate commonly used in biochemical assays to detect and measure the activity of the enzyme γ-glutamyl transpeptidase (GGT). GGT is an enzyme found in various tissues, including the liver, kidneys, and pancreas. It is involved in the breakdown and metabolism of glutathione, an important antioxidant in cells.

The compound is converted by GGT into a yellow-colored product, which can be quantified spectrophotometrically at a specific wavelength. The intensity of the color is directly proportional to the GGT activity in the sample. This allows for the measurement of GGT activity levels, which can help in assessing liver function and diagnosing liver diseases.

The application of γ-L-Glutamyl-3-carboxy-4-nitroanilide, monoammonium salt in GGT assays is useful in various contexts, including clinical diagnostics, research studies, and drug development. It enables the monitoring of GGT activity in patient samples, contributing to the identification and evaluation of liver diseases such as alcoholic liver disease, liver cancers, and drug-induced liver damage.

 

Product Packing:

试剂包装2

Additional Information:

Composition C12H16N4O7
Assay 99%
Appearance Yellow green powder
CAS No. 63699-78-5
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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