1-(3-Aminophenyl)-3-oxocyclobutane-1-carboxylic acid CAS:1698413-24-9

As a versatile building block, this molecule facilitates efficient medicinal chemistry and materials design. Reactions at the carboxylic acid furnish esters and amides while modifications of the amine systematically introduce diversity. Additionally, strained ring-opening reactions generate targeted analogs. These transformations produce focused libraries applicable for exploring structure-activity relationships and structure-property optimization. The acid also enables surface functionalization and polymer synthesis. It further serves as an intermediate in agrochemical research through tailored additions and substitutions. Therefore, through strategic manipulation of its distinct reactive sites, this synthon supports versatile generation of pharmaceuticals, functional materials and agricultural chemicals.