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1-(3-bromophenyl)-3,3-dimethoxycyclobutane-1-carbonitrile CAS:1494527-01-3

1-(3-bromophenyl)-3,3-dimethoxycyclobutane-1-carbonitrile is a cyano-substituted cyclobutane derivative containing an aryl bromide and two methoxy groups. This structural motif engages in nucleophilic substitution and addition reactions through the aryl halide and nitrile functionality.


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Application and Effect:

As a versatile building block, this compound facilitates efficient synthesis of pharmaceuticals, polymers and functional materials. Nucleophilic substitutions on the aryl bromide systematically introduce diversity for biological screening and structure activity elucidation. Additionally, homologations of the nitrile group furnish varied primary amines and acids. These transformations produce focused compound libraries in a rapid, regulated manner. Furthermore, the rigid cyclobutane supports metal-catalyzed couplings to furnish novel heterocyclic frameworks. The nitrile also renders this suitable as a monomer for developing specialty copolymers. Varying substituents provides control of material solubility, stability and properties. Therefore, owing to its multiple reactive sites, this synthon enables versatile generation of drug-like molecules, materials precursors and other value-added chemicals through simple manipulation of functional handles.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C13H14BrNO2
Assay 99%
Appearance white powder
CAS No.  1494527-01-3
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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