1-(4-aminophenyl)-Cyclopropanecarbonitrile CAS:108858-86-2

1-(4-aminophenyl)-Cyclopropanecarbonitrile has several important applications in organic synthesis and medicinal chemistry. Here are some common uses of this compound: Medicinal Chemistry: The compound serves as a valuable building block for the synthesis of biologically active compounds. It can be utilized in the development of potential drugs targeting various therapeutic areas such as cancer, inflammation, or neurological disorders. Cyclopropane Derivatives: 1-(4-aminophenyl)-Cyclopropanecarbonitrile can be used as a starting material to synthesize other cyclopropane derivatives. Cyclopropane-containing compounds often exhibit unique biological activities and can serve as scaffolds for drug discovery. Anticancer Agents: The compound's structure and reactivity make it suitable for developing potential anticancer agents. The presence of an aromatic amino group and a nitrile group allows for modifications that can enhance cytotoxicity against cancer cells or target specific cancer-related pathways. Pharmacological Studies: 1-(4-aminophenyl)-Cyclopropanecarbonitrile can be used in pharmacological studies to investigate its biological activity or evaluate its potential as a lead compound. It can be screened against various targets to assess its effects and mechanisms of action. Chemical Biology: The compound finds utility in chemical biology studies aiming to investigate biological processes and identify targets for therapeutic intervention. Its incorporation into small molecules or probes enables the exploration of specific cellular pathways or interactions. Heterocycle Synthesis: The compound can undergo reactions to form heterocycles, which are core structures found in many biologically active compounds. These heterocyclic derivatives can have diverse pharmacological properties and find applications in drug discovery. Aromatic Amine Reactions: The presence of an aromatic amine moiety in the compound allows for various reactions, such as nucleophilic substitution or condensation, to introduce different functional groups or modify the compound's properties. Lead Optimization: 1-(4-aminophenyl)-Cyclopropanecarbonitrile can serve as a starting point for lead optimization through structure-activity relationship studies. Modifications to the cyclopropane or phenyl ring can be explored to enhance potency, selectivity, or pharmacokinetic properties of potential drug candidates. In summary, 1-(4-aminophenyl)-Cyclopropanecarbonitrile is a versatile compound with various applications in organic synthesis and medicinal chemistry. It plays a critical role in medicinal chemistry, cyclopropane derivatives, anticancer agent development, pharmacological studies, chemical biology, heterocycle synthesis, aromatic amine reactions, and lead optimization. The compound's high purity, stability, and ability to modify molecules make it valuable in the development of biologically active compounds and the exploration of biological mechanisms.