1-(4-Fluorophenyl)piperazine CAS:2252-63-3
1-(4-Fluorophenyl)piperazine, represented by the chemical formula C10H12FN, is a derivative of piperazine, a bicyclic amine widely recognized for its diverse biological activities. The presence of a para-fluorophenyl substituent at the 1-position of the piperazine ring significantly alters the compound's electronic properties and lipophilicity, potentially enhancing its affinity for biological targets. The introduction of a fluorine atom into the phenyl group can modify the molecule’s interactions with receptors and enzymes, making 1-(4-fluorophenyl)piperazine a promising candidate in drug discovery. Fluorinated compounds often exhibit improved metabolic stability and may demonstrate increased potency compared to their non-fluorinated counterparts. This characteristic is particularly advantageous in the development of pharmaceuticals targeting central nervous system disorders, including anxiety, depression, and schizophrenia. Research has shown that piperazine derivatives can act as serotonin receptor modulators, dopamine receptor antagonists, and analgesics, among other roles. The unique combination of the piperazine core and the fluorophenyl substituent in 1-(4-fluorophenyl)piperazine positions it as a potential lead compound for the design of novel therapeutic agents. This compound can also serve as a versatile intermediate in organic synthesis, allowing for further modifications to create a variety of derivatives tailored for specific biological activities. Moreover, the synthetic routes leading to 1-(4-fluorophenyl)piperazine can be adapted to incorporate additional functional groups, expanding its applicability in medicinal chemistry. Ongoing studies are focused on elucidating the structure-activity relationships of this compound and its derivatives, aiming to optimize their efficacy and safety profiles. In summary, 1-(4-fluorophenyl)piperazine represents a valuable platform in the field of medicinal chemistry. Its distinctive structure and biological potential make it an important subject of research, with implications for developing innovative treatments for mental health disorders and beyond. Continued exploration of this compound may lead to significant advancements in therapeutic options available for patients.
Composition | C10H13FN2 |
Assay | 99% |
Appearance | white powder |
CAS No. | 2252-63-3 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |