1-(4-Nitrophenyl)cyclopropane-1-carbonitrile CAS:408328-42-7

1-(4-Nitrophenyl)cyclopropane-1-carbonitrile has several important applications in organic synthesis and pharmaceutical research. Here are some common uses of this compound: Medicinal Chemistry: The compound serves as a valuable building block for the synthesis of biologically active molecules. It can be utilized in the development of potential drugs targeting various therapeutic areas such as cancer, inflammation, or infectious diseases. Heterocyclic Chemistry: 1-(4-Nitrophenyl)cyclopropane-1-carbonitrile's cyclopropane scaffold makes it useful in heterocyclic chemistry. It can serve as a starting material for the synthesis of diverse heterocyclic compounds, which are valuable in drug discovery and development. Drug Design: Researchers employ this compound in structure-based drug design to explore new chemical space and develop novel drug candidates. By modifying different regions of the molecule, they can optimize its potency, selectivity, and other pharmacological properties. Carbonitrile Group Reactions: The carbonitrile group in this compound enables various reactions, including nucleophilic substitution, addition, and condensation reactions. It can be utilized to introduce additional functionalities or linkers into a molecule. Aromatic Nitration: The nitrophenyl group in 1-(4-Nitrophenyl)cyclopropane-1-carbonitrile is highly reactive towards nitration reactions. It can be selectively nitrated using appropriate reagents to introduce nitro groups at specific positions, allowing access to new derivatives. Bioconjugation: This compound can be used in bioconjugation strategies for labeling or modifying biomolecules. Its reactivity can be harnessed to attach various tags, fluorophores, or affinity handles to proteins, peptides, or nucleic acids. Chemical Biology: 1-(4-Nitrophenyl)cyclopropane-1-carbonitrile finds utility in chemical biology studies aiming to investigate biological processes and identify targets for therapeutic intervention. Its incorporation into small molecules or probes enables the exploration of specific cellular pathways or interactions. In summary, 1-(4-Nitrophenyl)cyclopropane-1-carbonitrile is a versatile compound with various applications in organic synthesis and pharmaceutical research. It plays a critical role in medicinal chemistry, heterocyclic chemistry, drug design, carbonitrile group reactions, aromatic nitration, bioconjugation, and chemical biology. The compound's high purity, stability, and reactivity make it valuable in the development of biologically active compounds and the exploration of biological mechanisms.