1-Bromo-4-chlorobutane CAS:6940-78-9

1-Bromo-4-chlorobutane (C4H8BrCl) features a four-carbon butane chain with a bromine atom attached to the first carbon and a chlorine atom on the fourth carbon. This arrangement qualifies it as a primary alkyl halide, presenting distinct physical and chemical properties characteristic of such compounds. As a colorless liquid, 1-bromo-4-chlorobutane has a moderate boiling point and low volatility compared to smaller alkyl halides, primarily due to its halogen content and molecular weight. The synthesis of 1-bromo-4-chlorobutane can be achieved through multiple methods, including the simultaneous halogenation of 1-bromobutane or 1-chlorobutane under specific conditions. Alternatively, it can be synthesized by reacting 1-bromobutane with a chlorinating agent, such as thionyl chloride (SOCl2), leading to the formation of this compound. These synthetic pathways make it accessible for laboratory and industrial purposes. In organic chemistry, 1-bromo-4-chlorobutane serves as a vital intermediate for synthesizing more complex molecules. The presence of both bromine and chlorine atoms makes it particularly reactive, allowing it to undergo various nucleophilic substitution reactions. These reactions enable the formation of new carbon–carbon bonds and facilitate the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Furthermore, 1-bromo-4-chlorobutane's dual halogen functionality enhances its reactivity profile, making it a valuable reagent in studies of reaction mechanisms and stereochemistry. Its application extends into material science, where it may be used to modify polymer properties. While handling 1-bromo-4-chlorobutane, safety precautions are essential due to its flammability and potential health hazards from exposure. Proper protective equipment and adherence to safety protocols must be observed to minimize risks. In summary, 1-bromo-4-chlorobutane is a significant compound with diverse applications, emphasizing its importance in advancing various fields of chemistry.