1-Bromohexadecane CAS:112-82-3

1-Bromohexadecane (C16H33Br) is a straight-chain, primary alkyl bromide notable for having a bromine atom bonded to the terminal carbon of a hexadecane backbone. This structural configuration classifies it within the alkyl halide family and imparts specific physical and chemical properties that are characteristic of this group. As a colorless liquid, 1-bromohexadecane has a higher boiling point and lower volatility compared to shorter-chain analogs, largely due to its greater molecular mass. Its long hydrocarbon chain provides hydrophobic qualities, resulting in very low solubility in water while being highly soluble in various organic solvents. The synthesis of 1-bromohexadecane can be achieved through multiple methods, including the direct bromination of hexadecane under controlled conditions or by converting hexadecanol into the corresponding bromide using reagents like phosphorus tribromide or thionyl chloride. These synthetic pathways make 1-bromohexadecane readily available for laboratory and industrial use. In organic chemistry, 1-bromohexadecane serves as a crucial building block for synthesizing more complex compounds. Its bromine atom is reactive and can participate in nucleophilic substitution reactions, allowing it to react with a variety of nucleophiles to form new carbon-carbon bonds. This makes it particularly useful in synthesizing specialty chemicals, pharmaceuticals, and agrochemicals. Moreover, 1-bromohexadecane's properties enable its application in producing surfactants and emulsifiers, where its long carbon chain enhances surfactant efficacy and stability in formulations. While handling 1-bromohexadecane, safety precautions must be strictly observed due to its flammability and potential health hazards upon exposure. Proper protective equipment and adherence to safety guidelines are essential. Overall, 1-bromohexadecane is a significant compound with diverse applications, underscoring its importance in various areas of research and industry.