1,3,5-tri-O-benzoyl-alpha-D-ribofuranose CAS:22224-41-5
1,3,5-Tri-O-benzoyl-alpha-D-ribofuranose is a significant carbohydrate derivative used predominantly in organic synthesis and nucleoside chemistry. The structure consists of a ribofuranose ring with three benzoyl groups esterified at the 1, 3, and 5 positions. These protective benzoyl groups serve multiple purposes; they enhance the solubility of the compound in organic solvents and protect the hydroxyl functionalities from unwanted reactions during subsequent synthetic steps, thereby improving the overall yield and efficiency of chemical processes. As a protected form of ribose, 1,3,5-tri-O-benzoyl-alpha-D-ribofuranose acts as an important intermediate in the synthesis of various nucleosides and nucleotides. Nucleosides are essential building blocks of nucleic acids—DNA and RNA—playing crucial roles in genetic information storage and transfer. The ability to efficiently synthesize modified nucleosides allows researchers to explore new therapeutic compounds, including antiviral drugs and anticancer agents. The introduction of benzoyl protecting groups also enables selective deprotection strategies, allowing chemists to remove specific protecting groups under mild conditions while leaving others intact. This selectivity is particularly advantageous in multi-step synthetic pathways where control over functional group reactivity is paramount. Research on 1,3,5-tri-O-benzoyl-alpha-D-ribofuranose extends beyond conventional synthesis; it also has implications in the development of nucleic acid-based therapeutics, such as antisense oligonucleotides and RNA interference technologies. These therapies aim to target and modulate gene expression, offering potential treatments for various diseases, including cancer and genetic disorders. In summary, 1,3,5-tri-O-benzoyl-alpha-D-ribofuranose is a versatile and valuable compound in the field of carbohydrate chemistry. Its role as a protecting group and intermediate in nucleoside synthesis makes it indispensable for advancing research and developing novel therapeutic approaches in molecular biology and medicine.
Composition | C26H22O8 |
Assay | 99% |
Appearance | white powder |
CAS No. | 22224-41-5 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |