(1S,2S)-ethyl 2-(4-fluorophenyl)cyclopropanecarboxylate CAS:345891-24-9

As a versatile intermediate, (1S,2S)-ethyl 2-(4-fluorophenyl)cyclopropanecarboxylate enables efficient asymmetric synthesis of pharmaceuticals and biological probes. Stereoselective reactions at the carboxylate construct targeted diastereomers applicable for biological evaluation and structure-activity studies. The electron-withdrawing fluorine also facilitates reactivity and late-stage modifications. It serves as a monomer for chiral polymeric materials. Moreover, agrichemical intermediates may emerge from enantioselective derivatizations supplying stereochemically enriched building blocks. Therefore, through functionalization of its stereocenter and cyclopropane ring, this chiral synthon supports synthesis of drugs, agrochemicals and functional materials with well-defined stereochemistry.