2′-Bromoacetophenone CAS:2142-69-0

2'-Bromoacetophenone (C9H9BrO) is an aromatic ketone featuring a bromine atom at the ortho position relative to the acetophenone moiety. This compound is identified for its significance in organic synthesis, serving as a crucial intermediate in the preparation of various biologically active molecules. Its structure consists of a benzene ring substituted with a bromine atom and a carbonyl group (C=O), a configuration that imparts distinctive chemical reactivity. The presence of the bromine atom in 2'-bromoacetophenone enhances its electrophilic character, making it prone to nucleophilic substitution reactions. This property enables the compound to participate in a variety of synthetic pathways, including the synthesis of pharmaceuticals and agrochemicals. For example, 2'-Bromoacetophenone can undergo reactions such as Friedel-Crafts acylation and Suzuki coupling, contributing to the development of compounds with potential therapeutic applications. Moreover, the reactivity of 2'-bromoacetophenone can be modulated by the electronic effects of the substituents on the aromatic ring. This feature allows chemists to design specific reactions that yield desired products with improved efficacy. Its utility extends beyond standard organic synthesis, as it also finds application in material science and as a building block for functionalized polymers. In conclusion, the compound 2'-bromoacetophenone plays a pivotal role in contemporary organic synthesis, serving as a versatile reagent for producing a wide range of chemical entities. Its unique properties and reactivity make it a valuable compound in both academic research and industrial applications, contributing to innovations in the development of new therapeutic agents.