2′-Chloroacetophenone CAS:2142-68-9

2'-Chloroacetophenone (C9H7ClO) is a halogenated aromatic ketone that consists of a phenyl group with a carbonyl moiety (–C=O) flanked by an acetyl group and a chlorine atom in the ortho position. This unique structural arrangement imparts distinct chemical properties and reactivity, making it a significant compound in various domains, particularly organic synthesis and industrial applications. The presence of the chlorine atom in 2'-chloroacetophenone enhances its electrophilic character, facilitating the participation of the compound in nucleophilic substitution reactions. As a result, it can undergo various transformations, including substitution reactions to introduce different functional groups, which are crucial in the synthesis of more complex organic molecules. These capabilities make 2'-chloroacetophenone a useful intermediate in pharmaceutical synthesis, allowing for the development of active pharmaceutical ingredients (APIs) and other biologically active compounds. Moreover, 2'-chloroacetophenone is employed in the flavor and fragrance industry due to its aromatic characteristics. It can be used as a building block for synthesizing various flavoring agents and fragrances that enhance the sensory attributes of food, beverages, and personal care products. Its pleasant scent profile makes it valuable in designing products with desirable olfactory qualities. Additionally, 2'-chloroacetophenone is referenced in research contexts, including studies on reaction mechanisms and synthetic pathways involving aromatic compounds. Its behavior demonstrates the influence of substituents on reactivity and stability in organic chemistry. In summary, 2'-chloroacetophenone is an essential compound with a wide range of applications in organic synthesis, pharmaceuticals, and the fragrance industry. Its unique structure and reactivity highlight its significance in advancing research and practical applications across various fields of chemistry, reinforcing its role as a versatile building block in synthetic organic chemistry.