2-Ethylhexyl bromide CAS:18908-66-2

2-Ethylhexyl bromide, sometimes referred to as 2-bromo-2-ethylhexane, is an alkyl halide characterized by a bromine atom covalently bonded to the second carbon of an octane backbone, specifically a branched variant known as 2-ethylhexane. The molecular formula for 2-ethylhexyl bromide is C₈H₁₉Br, with a molecular weight of approximately 187.16 g/mol. It is typically encountered as a clear, colorless to pale yellow liquid with a mild odor, exhibiting low solubility in water but good solubility in organic solvents like ether, chloroform, and hexane. The primary application of 2-ethylhexyl bromide lies in its role as an alkylating agent in organic synthesis. The presence of the bromine atom allows for nucleophilic substitution reactions, where the bromine can be replaced by a variety of nucleophiles, such as amines or alkoxides. This property makes it a valuable tool for synthesizing alcohols, amines, and ethers, which are essential components in pharmaceuticals, agrochemicals, and fine chemicals. Moreover, 2-ethylhexyl bromide is often employed in the production of surfactants and emulsifying agents due to its hydrophobic characteristics. These surfactants play pivotal roles in numerous applications, including cleaning products, cosmetics, and agricultural formulations. In laboratory settings, researchers utilize 2-ethylhexyl bromide in cross-coupling reactions and other methodologies that require alkyl halides. Its ability to participate in various reaction pathways facilitates the construction of complex organic molecules. Despite its utility, it is essential to handle 2-ethylhexyl bromide with care, as exposure may cause irritation to the skin, eyes, and respiratory system. Proper safety measures, including protective equipment and adequate ventilation, should always be employed when working with this compound. In conclusion, 2-ethylhexyl bromide is a significant compound in synthetic organic chemistry, valued for its versatility as an alkylating agent and its applications in surfactant production. Its importance spans various industries, including pharmaceuticals and agriculture, underscoring the need for safe handling practices during its use.