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2-Hydroxy-5-nitropyridine CAS:5418-51-9

2-Hydroxy-5-nitropyridine is a compound of interest in medicinal chemistry, characterized by its distinct molecular structure and potential pharmacological applications. This introduction aims to delve into the synthesis, structural characteristics, and pharmaceutical significance of 2-Hydroxy-5-nitropyridine.


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Application and Effect:

The synthesis of 2-Hydroxy-5-nitropyridine typically involves strategic routes utilizing commercially available starting materials. Methods commonly include the nitration of 2-hydroxypyridine to introduce the nitro group at the 5-position. Essential analytical techniques such as NMR, IR, and mass spectrometry are employed to validate the compound's structure and purity. Molecularly, 2-Hydroxy-5-nitropyridine features a pyridine ring substituted with a hydroxyl group at the 2-position and a nitro group at the 5-position. This molecular arrangement presents opportunities for further chemical modifications and interactions with biological targets. Pharmacological Significance and Potential Applications The structural attributes of 2-Hydroxy-5-nitropyridine make it an intriguing candidate for pharmaceutical research. Pyridine derivatives have been extensively studied for various pharmacological activities, including antimicrobial, anti-inflammatory, and antitumor effects. The presence of both hydroxyl and nitro functionalities may contribute synergistically to its biological activity, potentially enhancing its efficacy and selectivity. 2-Hydroxy-5-nitropyridine holds promise as a scaffold for developing drug candidates targeting a range of diseases, including infectious diseases, inflammatory disorders, and cancer. Additionally, the combination of hydroxyl and nitro groups offers opportunities for structure-activity relationship studies to optimize pharmacological properties and improve therapeutic outcomes. In conclusion, 2-Hydroxy-5-nitropyridine presents a compelling molecular scaffold with significant pharmaceutical implications. Further exploration into its synthesis, pharmacology, and medicinal chemistry is essential for unlocking its full therapeutic potential and advancing its applications in drug discovery and development.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C5H4N2O3
Assay 99%
Appearance white powder
CAS No.  5418-51-9
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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