2-Hydroxyphenylboronic acid CAS:89466-08-0

2-Hydroxyphenylboronic acid, commonly abbreviated as HOPBA, has garnered attention for its role as a key building block in Suzuki-Miyaura cross-coupling reactions, facilitating the synthesis of various biaryl compounds. Additionally, its reactivity towards diols has led to its utilization in the development of glucose sensors, where it forms stable complexes with glucose molecules, enabling their detection. In pharmaceutical research, 2-hydroxyphenylboronic acid derivatives have shown promise as potential drug candidates due to their ability to target specific biological molecules, such as enzymes and receptors. Furthermore, their biocompatibility and low toxicity profiles make them attractive candidates for further exploration in medicinal chemistry. In materials science, HOPBA-containing polymers have been investigated for applications in drug delivery systems, molecular recognition, and sensing technologies. The incorporation of 2-hydroxyphenylboronic acid into polymer matrices imparts stimuli-responsive behavior, allowing for the controlled release of encapsulated drugs or the selective capture of target analytes. Moreover, the versatility of 2-hydroxyphenylboronic acid extends to the field of supramolecular chemistry, where it participates in the formation of self-assembled structures through non-covalent interactions, such as hydrogen bonding and π-π stacking. These supramolecular assemblies exhibit tunable properties, making them attractive for applications ranging from molecular sensors to organic electronics. In conclusion, 2-hydroxyphenylboronic acid represents a valuable tool in the realms of organic synthesis, pharmaceuticals, and materials science. Its unique chemical properties and versatile reactivity make it a sought-after compound for diverse applications, from drug discovery to advanced materials development. Further research into its synthetic methodologies and applications is poised to unlock its full potential in various scientific and technological endeavors.