2,4-Dibromonicotinic acid CAS:1269291-41-9

2,4-Dibromonicotinic acid is a significant organic compound characterized by its unique structure, which consists of a pyridine ring substituted with two bromine atoms at the 2- and 4- positions, along with a carboxylic acid functional group. Its molecular formula, C6H4Br2NO2, highlights the integration of halogenation and acidity within a heterocyclic framework, making it a noteworthy molecule in both synthetic and medicinal chemistry. The incorporation of bromine atoms into the nicotinic acid structure greatly enhances its reactivity. The electrophilic bromine atoms can participate in various chemical reactions, including nucleophilic substitutions and coupling reactions. As a result, 2,4-dibromonicotinic acid serves as a valuable intermediate for synthesizing a range of complex organic molecules, particularly in drug discovery and the development of agrochemicals. The presence of the carboxylic acid functional group further adds to its utility, enabling additional transformations, such as esterification and amidation. In medicinal chemistry, 2,4-dibromonicotinic acid has garnered attention for its potential biological activities. Compounds derived from this molecular framework can exhibit antimicrobial, anti-inflammatory, and anticancer properties, making them candidates for further investigation in therapeutic applications. Understanding the pharmacological profiles of these derivatives could aid in the development of novel drugs targeting various diseases. Moreover, the study of 2,4-dibromonicotinic acid contributes to broader areas of research, including the exploration of structure-activity relationships (SAR) in drug design. By modifying the bromine positions or replacing them with other functional groups, researchers can optimize the biological activity and selectivity of newly synthesized compounds. Overall, 2,4-dibromonicotinic acid exemplifies the importance of halogenated heterocycles in contemporary organic chemistry and drug development. Its reactivity and potential bioactivity open avenues for creating innovative compounds that address pressing health challenges.