2,4-Difluoro-3-methoxybenzoic acid CAS:178974-97-5

2,4-Difluoro-3-methoxybenzoic acid combines both halogenation and methoxylation, leading to a structure that exhibits unique chemical properties. Its molecular formula, C9H8F2O3, indicates the presence of two fluorine atoms that contribute significantly to its electronic behavior and lipophilicity. The carboxylic acid group (-COOH) demonstrates acidic properties, while the methoxy group (-OCH₃) provides a site for further chemical modifications. The incorporation of fluorine into organic molecules often enhances their biological activity and metabolic stability. For example, fluorinated compounds tend to exhibit increased affinity toward certain biological receptors, making them valuable in drug design. Specifically, 2,4-difluoro-3-methoxybenzoic acid may serve as a scaffold for developing pharmaceuticals targeting various diseases, including cancer and inflammatory disorders. From a synthetic perspective, this compound can be utilized as a versatile building block for creating more complex molecules. The presence of the carboxylic acid allows for straightforward derivatization through esterification or amidation reactions, enabling the formation of various esters and amides. Additionally, the methoxy group can undergo transformations such as demethylation or oxidation, providing access to further functional groups. Moreover, 2,4-difluoro-3-methoxybenzoic acid can act as a precursor in synthesizing agrochemicals or polymer additives, demonstrating its versatility across multiple fields. Research continues into optimizing syntheses of this compound and exploring its interactions with biological systems, underscoring its significance in contemporary chemical research. Overall, the multifaceted nature of 2,4-difluoro-3-methoxybenzoic acid makes it a promising candidate for advancing both pharmaceutical and material sciences.