2,4-Difluoroaniline CAS:367-25-9
2,4-Difluoroaniline, with the molecular formula C6H5F2N, is an important aromatic amine distinguished by its two fluorine substituents located at the ortho (2) and para (4) positions relative to the amino group (-NH2) on the benzene ring. This structural arrangement not only influences the compound's physical and chemical properties but also enhances its reactivity in various chemical reactions. One of the primary applications of 2,4-difluoroaniline lies in the pharmaceutical industry, where it serves as a crucial intermediate in synthesizing several therapeutic compounds. The presence of fluorine atoms in organic molecules often improves metabolic stability, lipophilicity, and bioavailability, making difluorinated compounds attractive in drug development. Consequently, 2,4-difluoroaniline is used to produce a range of biologically active substances, including anti-inflammatory agents, antibiotics, and cancer therapeutics. Additionally, 2,4-difluoroaniline finds applications in the agrochemical sector, where it is utilized as an intermediate in the synthesis of herbicides and pesticides. The introduction of fluorine can enhance the efficacy and selectivity of these agrochemicals, resulting in improved crop protection and yield. In synthetic chemistry, 2,4-difluoroaniline acts as a versatile building block for constructing more complex molecular architectures through various coupling reactions, such as Suzuki or Ullmann cross-couplings. Its ability to participate in electrophilic aromatic substitutions and other transformations further elevates its significance in organic synthesis. In summary, 2,4-difluoroaniline exemplifies the importance of fluorinated aromatic amines in contemporary chemical research and industry. Its diverse applications in pharmaceuticals, agrochemicals, and synthetic chemistry underscore its role as a valuable intermediate in developing innovative chemical entities. As research in drug discovery and agricultural science continues to evolve, 2,4-difluoroaniline remains an essential component in the quest for new, effective compounds.
Composition | C6H5F2N |
Assay | 99% |
Appearance | white powder |
CAS No. | 367-25-9 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |