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2,4-Difluoroaniline CAS:367-25-9

2,4-Difluoroaniline is an aromatic amine characterized by the presence of two fluorine atoms at the 2 and 4 positions of the aniline molecule. Its chemical formula is C6H5F2N, and it features both an amino group (-NH2) and fluorinated benzene ring. This compound has garnered attention in various fields, including pharmaceuticals and agrochemicals, due to its utility as an intermediate in the synthesis of bioactive molecules. The unique properties imparted by the fluorine substituents enhance the compound’s stability and reactivity, making it a valuable building block for developing novel chemical entities.


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Application and Effect:

2,4-Difluoroaniline, with the molecular formula C6H5F2N, is an important aromatic amine distinguished by its two fluorine substituents located at the ortho (2) and para (4) positions relative to the amino group (-NH2) on the benzene ring. This structural arrangement not only influences the compound's physical and chemical properties but also enhances its reactivity in various chemical reactions. One of the primary applications of 2,4-difluoroaniline lies in the pharmaceutical industry, where it serves as a crucial intermediate in synthesizing several therapeutic compounds. The presence of fluorine atoms in organic molecules often improves metabolic stability, lipophilicity, and bioavailability, making difluorinated compounds attractive in drug development. Consequently, 2,4-difluoroaniline is used to produce a range of biologically active substances, including anti-inflammatory agents, antibiotics, and cancer therapeutics. Additionally, 2,4-difluoroaniline finds applications in the agrochemical sector, where it is utilized as an intermediate in the synthesis of herbicides and pesticides. The introduction of fluorine can enhance the efficacy and selectivity of these agrochemicals, resulting in improved crop protection and yield. In synthetic chemistry, 2,4-difluoroaniline acts as a versatile building block for constructing more complex molecular architectures through various coupling reactions, such as Suzuki or Ullmann cross-couplings. Its ability to participate in electrophilic aromatic substitutions and other transformations further elevates its significance in organic synthesis. In summary, 2,4-difluoroaniline exemplifies the importance of fluorinated aromatic amines in contemporary chemical research and industry. Its diverse applications in pharmaceuticals, agrochemicals, and synthetic chemistry underscore its role as a valuable intermediate in developing innovative chemical entities. As research in drug discovery and agricultural science continues to evolve, 2,4-difluoroaniline remains an essential component in the quest for new, effective compounds.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C6H5F2N
Assay 99%
Appearance white powder
CAS No.  367-25-9
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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