(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid CAS:132622-69-6
Boc-D-proline serves as a cornerstone in peptide synthesis, particularly in the construction of peptide libraries and the production of peptide-based pharmaceuticals. Its chiral center imparts stereochemical control during peptide bond formation, crucial for the synthesis of biologically active peptides with defined three-dimensional structures. Moreover, the tert-butoxycarbonyl (Boc) protecting group shields the amino functionality, allowing for selective deprotection and subsequent peptide elongation. In drug discovery, Boc-D-proline facilitates the synthesis of peptidomimetics and cyclic peptides, which exhibit enhanced proteolytic stability and target specificity compared to linear peptides. Its incorporation into peptide structures can modulate pharmacokinetic properties and improve biological activity, making it valuable in the development of peptide therapeutics targeting various diseases, including cancer, infectious diseases, and metabolic disorders. Furthermore, Boc-D-proline finds applications in the synthesis of natural products, asymmetric catalysis, and the preparation of peptide-based molecular probes for biological studies. Its versatility and reliability make it an indispensable tool for chemists and researchers striving to access complex peptide architectures and explore their therapeutic potential. Overall, Boc-D-proline stands as a fundamental component in peptide chemistry, enabling the synthesis of diverse peptide structures with tailored functionalities, essential for advancing both basic research and drug discovery efforts.
Composition | C10H18N2O4 |
Assay | 99% |
Appearance | white powder |
CAS No. | 132622-69-6 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |