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(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid CAS:132622-69-6

(2S,4R)-4-amino-1-[(tert-butoxy)carbonyl]pyrrolidine-2-carboxylic acid, commonly known as Boc-D-proline, is a vital compound in organic synthesis and peptide chemistry. Its structure features a pyrrolidine ring with a tert-butoxycarbonyl (Boc) protected amino acid moiety, offering versatile reactivity for peptide bond formation and stereochemical control. This compound plays a crucial role in peptide synthesis strategies, enabling the creation of peptide-based therapeutics, peptidomimetics, and biochemical probes. Its chirality and stability make it a preferred building block in pharmaceutical research and drug development endeavors.


Product Detail

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Application and Effect:

Boc-D-proline serves as a cornerstone in peptide synthesis, particularly in the construction of peptide libraries and the production of peptide-based pharmaceuticals. Its chiral center imparts stereochemical control during peptide bond formation, crucial for the synthesis of biologically active peptides with defined three-dimensional structures. Moreover, the tert-butoxycarbonyl (Boc) protecting group shields the amino functionality, allowing for selective deprotection and subsequent peptide elongation. In drug discovery, Boc-D-proline facilitates the synthesis of peptidomimetics and cyclic peptides, which exhibit enhanced proteolytic stability and target specificity compared to linear peptides. Its incorporation into peptide structures can modulate pharmacokinetic properties and improve biological activity, making it valuable in the development of peptide therapeutics targeting various diseases, including cancer, infectious diseases, and metabolic disorders. Furthermore, Boc-D-proline finds applications in the synthesis of natural products, asymmetric catalysis, and the preparation of peptide-based molecular probes for biological studies. Its versatility and reliability make it an indispensable tool for chemists and researchers striving to access complex peptide architectures and explore their therapeutic potential. Overall, Boc-D-proline stands as a fundamental component in peptide chemistry, enabling the synthesis of diverse peptide structures with tailored functionalities, essential for advancing both basic research and drug discovery efforts.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C10H18N2O4
Assay 99%
Appearance white powder
CAS No.  132622-69-6
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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