3-(2-Fluoro-phenyl)-isoxazole-5-carbaldehyde CAS:808740-52-5

This compound demonstrates versatility for syntheses of pharmaceuticals, agrochemicals, and functional materials. The aldehyde is amenable to Wittig, Grignard, and hydride reductions yielding primary alcohols and amines. It also undergoes additions with organometallic reagents and nucleophiles to form substituted alcohols. The formyl group enables imine and ketal/acetal formations. Furthermore, derivatization of the isoxazole ring and fluorine substitution expand molecular diversity. This establishes it as a critical building block, while the unique structure lends itself to agrochemical and drug discovery efforts targeting analog series. Beyond small molecules, this aldehyde is also suitable for producing specialty polymers with tunable optical and electronic attributes.