3-Benzylimidazo[1,5-a]pyridine-1-carboxylic acid CAS:1018517-02-6

As a versatile building block, this synthon facilitates efficient synthesis of pharmaceuticals and functional materials. Reactions at the heterocyclic nitrogen systematically introduce diversity for biological evaluation. Additionally, conversions of the carboxylic acid to varied esters, amides and other derivatives produce analog libraries. These transformations rapidly furnish focused collections applicable to different therapeutic areas. The benzyl substitution also enables metal-catalyzed cross-couplings. Meanwhile, the acid group allows surface functionalization and polymerization for tailored materials. It further serves as a common intermediate in agrochemical design through additional reactions. Therefore, with multiple points of reactivity, this building block supports versatile generation of drugs, specialty polymers and crop protection agents through strategic diversification of its functional moieties.