3-CHLOROMETHYL-1-METHYL-1H-[1,2,4]TRIAZOLE CAS:135206-76-7
The synthesis of 2-chloro-5-iodobenzoic acid involves a multi-step procedure starting from benzoic acid. First, the benzoic acid is brominated at the 2 position using an appropriate brominating agent. Subsequently, the brominated intermediate is treated with an iodine source under controlled conditions to introduce the iodine atom at the 5 position. Finally, the resulting 2-bromo-5-iodobenzoic acid is converted to 2-chloro-5-iodobenzoic acid through a substitution reaction with chloride ions. Due to its structural features, 2-chloro-5-iodobenzoic acid is a versatile building block in the synthesis of various derivatives, including pharmaceuticals and agrochemicals. Its presence of both halogen atoms allows for further functionalization, such as coupling reactions to form more complex molecules. Moreover, the carboxylic acid group provides a handle for further modifications, such as esterification or amidation, to tailor its properties for specific applications. Research into 2-chloro-5-iodobenzoic acid also extends to its potential use as a reagent in organic synthesis. Its reactivity can be exploited in various transformations, such as nucleophilic aromatic substitution, where the halogen atoms can be replaced with other substituents. Additionally, the carboxylic acid group can be involved in decarboxylation reactions to generate arynes, which are highly reactive intermediates used in the synthesis of complex organic molecules. In summary, 2-chloro-5-iodobenzoic acid is a valuable organic compound with diverse applications in medicinal chemistry, material science, and organic synthesis. Its synthesis and reactivity make it a versatile building block for the preparation of a wide range of compounds, and ongoing research continues to explore its potential uses and applications in the field of organic chemistry.
Composition | C7H4ClIO2 |
Assay | 99% |
Appearance | white powder |
CAS No. | 19094-56-5 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |