4(1H)-Pyrimidinone,5-fluoro-2-methoxy-,hydrazone CAS:166524-64-7

4(1H)-Pyrimidinone, 5-fluoro-2-methoxy-, hydrazone is a compound of significant interest in heterocyclic chemistry, primarily due to its unique combination of structural features and functional groups. The compound consists of a pyrimidinone ring, characterized by two nitrogen atoms in a six-membered aromatic system, which is known for its diverse biological activities. The introduction of a fluoro group at the 5-position enhances the compound's lipophilicity and metabolic stability, often leading to improved pharmacokinetic properties compared to non-fluorinated analogs. The methoxy group at the 2-position further contributes to the compound's overall chemical behavior, potentially influencing its solubility and interaction with biological targets. Hydrazones are formed through the reaction of carbonyl-containing compounds with hydrazines, resulting in a linkage that is typically reactive and can undergo further transformations. In the case of 4(1H)-pyrimidinone, 5-fluoro-2-methoxy-, this hydrazone functionality makes it suitable for a variety of reactions, including oxidation, reduction, and cyclization, allowing for the synthesis of a range of derivatives. In medicinal chemistry, pyrimidinone derivatives have been explored for their potential therapeutic effects, including antiviral, anticancer, and anti-inflammatory actions. The ability to modify the hydrazone component allows researchers to tailor the compound’s biological activity for specific therapeutic targets. Preliminary studies suggest that derivatives of this compound may possess significant biological activity, making it a promising candidate for further research. Moreover, the reactivity of hydrazones can be exploited in designing novel drug candidates, particularly those aimed at overcoming drug resistance in pathogens. Given the ongoing need for new therapeutics, 4(1H)-pyrimidinone, 5-fluoro-2-methoxy-, hydrazone serves as an important scaffold in drug discovery, providing avenues for the development of innovative treatments. In conclusion, 4(1H)-pyrimidinone, 5-fluoro-2-methoxy-, hydrazone is a noteworthy compound with significant implications in pharmaceutical research, owing to its unique structure and potential biological activities.