3,4,5-Trifluorophenylboronic acid CAS:143418-49-9

3,4,5-Trifluorophenylboronic acid exhibits distinctive structural characteristics and versatile applications across various branches of chemistry. 1. Synthetic Chemistry: Suzuki-Miyaura Cross-Coupling: Widely utilized in Suzuki-Miyaura cross-coupling reactions, 3,4,5-trifluorophenylboronic acid facilitates the synthesis of biaryl compounds. Its versatility as a boronic acid reagent enables the construction of complex organic molecules crucial in pharmaceuticals, agrochemicals, and materials science. 2. Medicinal Chemistry: Drug Development: The presence of three fluorine atoms on the phenyl ring influences the compound's interactions with biological targets, making it valuable in drug discovery. Derivatives of 3,4,5-trifluorophenylboronic acid are explored for their potential as therapeutic agents targeting various diseases, including cancer, inflammation, and viral infections. Protein Labeling: Functionalized derivatives of this compound are utilized in the labeling of proteins, enabling the visualization and study of protein structures and interactions. 3. Materials Science: Polymer Modification: Incorporated into polymers, 3,4,5-trifluorophenylboronic acid derivatives modify properties such as solubility, thermal stability, and mechanical strength. These modified polymers find applications in coatings, adhesives, and biomedical materials. Organic Electronics: Due to its electron-withdrawing nature, this compound and its derivatives are employed in the fabrication of organic electronic devices, such as OLEDs and OFETs, for enhanced performance. 4. Organic Synthesis: Functional Group Compatibility: The trifluorophenyl group provides unique reactivity profiles, enabling selective transformations and compatibility with various functional groups in organic synthesis. This versatility allows for the synthesis of diverse organic molecules with precise control over structure and functionality. In summary, 3,4,5-trifluorophenylboronic acid is a versatile compound with wide-ranging applications in synthetic chemistry, medicinal chemistry, materials science, and organic synthesis. Its distinct structural features and reactivity offer opportunities for innovation and advancement across multiple scientific disciplines, contributing to the development of novel molecules, materials, and pharmaceutical agents.