(3alpha,5beta,6E)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oic acid CAS:1516887-33-4

(3alpha,5beta,6E)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oic acid finds applications in pharmaceutical research due to its structural attributes and potential pharmacological benefits. Here are its key uses: Cholestatic Liver Disorders: The compound is studied for its potential therapeutic effects in cholestatic liver diseases, where bile flow from the liver is impaired. It may help improve bile secretion and reduce liver damage associated with these conditions. Gallstone Dissolution: Research explores the compound's ability to dissolve gallstones, particularly cholesterol gallstones, by altering bile composition and promoting dissolution. Metabolic Syndrome: Studies investigate its role in metabolic syndrome, a cluster of conditions including obesity, insulin resistance, and high blood pressure. The compound's effects on lipid metabolism and insulin sensitivity are under scrutiny for potential therapeutic applications. Anti-inflammatory Properties: (3alpha,5beta,6E)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oic acid may possess anti-inflammatory effects. Research aims to understand its potential in modulating inflammatory pathways implicated in various diseases, including inflammatory bowel disease and arthritis. Gastrointestinal Disorders: Its structural features suggest potential benefits in gastrointestinal disorders such as irritable bowel syndrome (IBS) and Crohn's disease. Studies aim to elucidate its effects on gut motility and inflammation. Hepatic Fibrosis: The compound is investigated for its ability to prevent or reduce hepatic fibrosis, a condition characterized by excessive collagen deposition in the liver. It may inhibit fibrogenesis and promote liver tissue regeneration. Bile Acid Receptor Agonist: As a bile acid derivative, it serves as a tool compound in pharmacological research targeting bile acid receptors. This facilitates the study of bile acid signaling pathways and their role in metabolic and liver disorders. Drug Development: Beyond therapeutic uses, (3alpha,5beta,6E)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oic acid serves as a starting point for developing novel pharmaceuticals. Its unique structure and pharmacological profile make it valuable in discovering new drugs for treating a wide range of diseases. In summary, (3alpha,5beta,6E)-6-Ethylidene-3-hydroxy-7-oxocholan-24-oic acid is a versatile compound with diverse potential applications in pharmaceutical research. Its distinctive chemical structure and biological activities offer opportunities for developing innovative therapies across various medical fields, from liver diseases to metabolic disorders and beyond.