(3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid CAS:2624378-54-5

(3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid has several important applications in organic synthesis and pharmaceutical research. Here are some common uses of this compound: Medicinal Chemistry: The compound serves as a valuable building block for the synthesis of biologically active molecules. It can be utilized in the development of potential drugs targeting various therapeutic areas such as central nervous system disorders, cardiovascular diseases, or infectious diseases. Heterocyclic Chemistry: (3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid's pyrrolidine scaffold makes it useful in heterocyclic chemistry. It can serve as a starting material for the synthesis of diverse heterocyclic compounds, which are valuable in drug discovery and development. Peptide Synthesis: The Boc protecting group in this compound enables its use in solid-phase peptide synthesis. It can protect the amino group of an amino acid during peptide assembly, allowing for the stepwise elongation of peptides with desired sequences. Proline Derivative: (3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid is a proline derivative and can be used to introduce proline residues into peptide or small molecule structures. Proline residues play crucial roles in peptide conformation and can influence biological activity. Drug Design: Researchers employ this compound in structure-based drug design to explore new chemical space and develop novel drug candidates. By modifying different regions of the molecule, they can optimize its potency, selectivity, and other pharmacological properties. Chemical Biology: (3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid finds utility in chemical biology studies aiming to investigate biological processes and identify targets for therapeutic intervention. Its incorporation into small molecules or probes enables the exploration of specific cellular pathways or interactions. Protein Modification: The carboxylic acid group in this compound allows for protein modification studies. It can be utilized to selectively label proteins, introduce reactive groups for conjugation, or modify specific amino acid residues for functional studies. In summary, (3S,4R)-1-Boc-4-methyl-pyrrolidine-3-carboxylic acid is a versatile compound with various applications in organic synthesis and pharmaceutical research. It plays a critical role in medicinal chemistry, heterocyclic chemistry, peptide synthesis, proline derivatives, drug design, chemical biology, and protein modification. The compound's high purity, stability, and ability to modify molecules make it valuable in the development of biologically active compounds and the exploration of biological mechanisms.