(3S,4R)-4-Methylpyrrolidine-3-carboxylic acid CAS:2165614-75-3

(3S,4R)-4-Methylpyrrolidine-3-carboxylic acid has several important applications in organic synthesis and pharmaceutical research. Here are some common uses of this compound: Medicinal Chemistry: The compound serves as a building block for the synthesis of biologically active molecules. It can be utilized in the development of potential therapeutic agents targeting various diseases such as neurological disorders, cancer, or bacterial infections. Asymmetric Synthesis: (3S,4R)-4-Methylpyrrolidine-3-carboxylic acid possesses a chiral center at the 3rd carbon, making it valuable in asymmetric synthesis. Its unique stereochemistry allows for the creation of enantiomerically pure compounds, which are crucial in drug discovery and development. Peptide Synthesis: The carboxylic acid group in this compound makes it useful for peptide synthesis. It can be incorporated into peptide chains during solid-phase peptide synthesis, enabling the introduction of diverse functionalities or modification of peptide sequences. Protein Structure Studies: Researchers employ (3S,4R)-4-Methylpyrrolidine-3-carboxylic acid as a structural probe in studies aiming to determine protein folding patterns or investigate protein-ligand interactions. It can serve as a non-natural amino acid substitute, allowing for the design and characterization of modified proteins. Pharmacokinetic Studies: This compound can be utilized in pharmacokinetic studies to evaluate absorption, distribution, metabolism, and excretion properties of drugs. By incorporating (3S,4R)-4-Methylpyrrolidine-3-carboxylic acid into drug candidates, researchers can gain insight into their behavior within living organisms. Chemical Biology: (3S,4R)-4-Methylpyrrolidine-3-carboxylic acid finds utility in chemical biology studies aiming to understand biological processes and develop tools for cell imaging or target identification. Its incorporation into small molecules or probes enables the investigation of specific cellular pathways or interactions. In summary, (3S,4R)-4-Methylpyrrolidine-3-carboxylic acid is a versatile compound with various applications in organic synthesis and pharmaceutical research. It plays a critical role in medicinal chemistry, asymmetric synthesis, peptide synthesis, and protein structure studies. Additionally, it finds use in pharmacokinetic studies and chemical biology research. The compound's high purity, stability, and ability to introduce chirality make it valuable in the development of biologically active compounds and the exploration of biological mechanisms.