4-[(2Z)-3-(3,5-dichlorophenyl)-4,4,4-trifluoro-1-oxo-2-buten-1-yl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-Benzamide CAS:943436-93-9

The compound can be synthesized through a multi-step synthetic route. One possible approach involves the use of a Suzuki coupling reaction to join together the 3,5-dichlorophenylboronic acid and the 2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]benzamide. The Suzuki coupling is a palladium-catalyzed cross-coupling reaction that allows for the formation of a C-C bond between two aryl fragments. Another step in the synthesis could involve the use of a Horner-Wadsworth-Emmons (HWE) reaction to construct the alpha,beta-unsaturated ketone. The HWE reaction is a nucleophilic addition/elimination reaction that can be used to convert an aldehyde or ketone into an alpha,beta-unsaturated ketone in the presence of a phosphonate ester and a strong base. The final product, 4-[(2Z)-3-(3,5-dichlorophenyl)-4,4,4-trifluoro-1-oxo-2-buten-1-yl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-Benzamide, can be purified through recrystallization or column chromatography. The compound can be further modified or functionalized to create more complex molecules. For instance, the amide group can be converted into other functional groups such as esters or amides, or the trifluoroethylamide group can be further functionalized. 4-[(2Z)-3-(3,5-dichlorophenyl)-4,4,4-trifluoro-1-oxo-2-buten-1-yl]-2-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-Benzamide has potential applications in the pharmaceutical and agrochemical industries. The presence of the trifluoroethylamine group and the alpha,beta-unsaturated ketone make it a valuable intermediate for the synthesis of bioactive compounds. Additionally, the compound could be used as a precursor for the synthesis of other complex molecules with potential biological activity. The compound should be handled with care and stored under appropriate conditions to maintain its stability and purity.