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4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one CAS:10212-20-1

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one is a complex nucleoside analog that features a pyrimidine base attached to a modified ribose sugar. The presence of a fluorine atom and hydroxyl groups in its structure enhances its biochemical properties, making it an interesting candidate for antiviral and anticancer research. This compound has potential applications in medicinal chemistry, particularly as a therapeutic agent targeting nucleic acid synthesis and metabolic pathways in pathogenic organisms. Its unique structural characteristics allow for better interaction with biological targets involved in DNA and RNA metabolism.


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Application and Effect:

4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one is a sophisticated nucleoside analog characterized by the integration of a pyrimidine base and a uniquely modified sugar moiety. The modification includes a fluorine substituent at the 3' position and hydroxyl groups that enhance solubility and stability. Such structural alterations are essential for increasing the compound's bioactivity and specificity in interacting with biological macromolecules. The primary mechanism of action for this compound involves its incorporation into nucleic acids, where it can disrupt normal DNA and RNA synthesis. By mimicking natural nucleotides, it interferes with the function of key enzymes involved in nucleotide metabolism, potentially inhibiting viral replication or tumor growth. For instance, this compound may target viral polymerases or replication machinery in cancer cells, providing a dual approach to treating infectious diseases and malignancies. Additionally, the enhanced stability provided by the fluorine substitution contributes to greater resistance against enzymatic degradation, allowing for prolonged activity within biological systems. This characteristic makes it attractive for therapeutic development, as it could lead to more effective treatments requiring lower dosages and less frequent administration. Research into this compound’s efficacy is ongoing, focusing on its potential applications in antiviral therapies, particularly against RNA viruses, as well as in oncology for the treatment of specific cancers that rely on aberrant nucleic acid metabolism. Understanding how this nucleoside analog interacts at the molecular level will help elucidate its full therapeutic potential. In summary, 4-Amino-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one represents a promising avenue for innovation in drug design, showcasing how modifications to nucleoside structures can yield compounds with significant biological activities and therapeutic implications.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C9H12FN3O4
Assay 99%
Appearance white powder
CAS No.  10212-20-1
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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