4-Carboxyphenylboronic acid CAS:14047-29-1

4-Carboxyphenylboronic acid (4-CPBA) is a versatile compound with a boronic acid functional group attached to a phenyl ring, substituted with a carboxylic acid group at the para position. This molecular structure confers several unique properties and applications. 1. Synthetic Applications: Suzuki-Miyaura Cross-Coupling: 4-CPBA is widely utilized in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds. This reaction is crucial in the synthesis of various pharmaceuticals, agrochemicals, and functional materials. 2. Sensing and Analytical Chemistry: Diol and Sugar Binding: Due to its boronic acid moiety, 4-CPBA exhibits high affinity for diols and sugars. This property is exploited in the development of sensors for glucose monitoring, environmental monitoring, and drug delivery systems. 3. Medicinal Chemistry: Enzyme Inhibition: 4-CPBA and its derivatives are investigated for their potential as enzyme inhibitors. By modulating enzyme activity, they hold promise in the treatment of various diseases, including cancer, diabetes, and microbial infections. Receptor Ligands: The ability of 4-CPBA to interact with biological receptors makes it valuable in designing ligands for receptors involved in signal transduction, neurotransmission, and hormone regulation. 4. Material Science: Functional Materials: 4-CPBA and its derivatives are incorporated into polymers and materials for imparting specific properties such as adhesion, conductivity, and optical activity. These materials find applications in electronics, coatings, and biocompatible substrates. In conclusion, 4-Carboxyphenylboronic acid is a multifunctional compound with diverse applications ranging from synthetic chemistry to sensing, medicinal chemistry, and material science. Its unique structure and properties continue to drive research and innovation in various fields.