4-Chloro-2-fluoro-3-methoxyphenylboronic acid CAS:944129-07-1

4-Chloro-2-fluoro-3-methoxyphenylboronic acid exhibits distinct structural attributes and diverse applications across various branches of chemistry. 1. Synthetic Chemistry: Suzuki-Miyaura Cross-Coupling: This compound is extensively utilized in Suzuki-Miyaura cross-coupling reactions, facilitating the construction of biaryl compounds. Its versatility as a boronic acid reagent enables the synthesis of complex organic molecules crucial in pharmaceuticals, agrochemicals, and materials science. 2. Medicinal Chemistry: Drug Design: The unique arrangement of substituents in 4-chloro-2-fluoro-3-methoxyphenylboronic acid influences its interactions with biological targets, making it valuable in drug discovery. Derivatives of this compound are investigated for their potential as therapeutic agents targeting various diseases, including cancer, inflammatory disorders, and microbial infections. Molecular Imaging: Functionalized derivatives of this compound are explored for their use in molecular imaging techniques, aiding in the visualization and understanding of biological processes in living organisms. 3. Materials Science: Organic Electronics: 4-Chloro-2-fluoro-3-methoxyphenylboronic acid derivatives find applications in organic electronic devices, such as organic light-emitting diodes (OLEDs) and organic photovoltaic cells (OPVs), owing to their electron-rich nature and tailored electronic properties. Polymer Synthesis: Functionalized derivatives of this compound are incorporated into polymers to modulate their properties, such as solubility, conductivity, and thermal stability, for applications in coatings, adhesives, and biomedical materials. 4. Organic Synthesis: Functional Group Tolerance: The chloro, fluoro, and methoxy substituents on the phenyl ring provide diverse reactivity profiles, enabling selective transformations and compatibility with various functional groups in organic synthesis. This versatility allows for the preparation of complex molecules with precise control over structure and functionality. In summary, 4-chloro-2-fluoro-3-methoxyphenylboronic acid is a versatile compound with wide-ranging applications in synthetic chemistry, medicinal chemistry, materials science, and organic synthesis. Its unique structural features and reactivity offer opportunities for innovation and advancement across multiple scientific disciplines, contributing to the development of novel molecules, materials, and pharmaceutical agents.