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4-CHLOROPHENYL CHLOROFORMATE CAS:7693-45-0

4-Chlorophenyl chloroformate is an important organic compound utilized in various synthetic chemistry applications. This compound contains a 4-chlorophenyl group linked to a chloroformate functional group, making it a valuable reagent for acylation reactions. The presence of the chlorine atom increases the electrophilicity of the carbonyl carbon, facilitating nucleophilic attacks by alcohols and amines. Due to its reactivity, 4-chlorophenyl chloroformate finds extensive use in pharmaceutical synthesis, agrochemical development, and the production of complex organic molecules. Understanding its properties and behaviors is essential for chemists aiming to effectively utilize this versatile compound in their research.


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Application and Effect:

4-Chlorophenyl chloroformate (C8H6ClO2) is a reactive compound widely employed in organic synthesis. It comprises a chloroformate functional group attached to a 4-chlorobenzene ring, which enhances its reactivity by increasing the electrophilic character of the carbonyl carbon. This attribute makes it particularly useful as an acylating agent, enabling the formation of esters and carbamates through nucleophilic substitution reactions with alcohols and amines. One of the most significant applications of 4-chlorophenyl chloroformate is in the synthesis of biologically active compounds. The ability to introduce the 4-chlorophenyl moiety into target molecules can significantly alter their pharmacological properties, enhancing bioactivity or modulating selectivity. In pharmaceutical research, this compound is frequently used to create intermediates for drug candidates and other therapeutically active substances. In addition to its role in acylation reactions, 4-chlorophenyl chloroformate serves as a protecting group for functional groups like alcohols and amines during multi-step organic syntheses. By temporarily modifying these reactive sites, chemists can control reaction pathways more effectively, allowing for the selective construction of complex molecules. The removal of the protecting group under mild conditions further enhances its utility. Despite its advantages, caution is necessary when handling 4-chlorophenyl chloroformate due to its irritant properties and potential toxicity. Appropriate safety measures, such as using personal protective equipment and conducting reactions in a fume hood, are essential. In conclusion, 4-chlorophenyl chloroformate is a crucial reagent in the arsenal of synthetic chemists, facilitating the creation of complex organic structures essential for advancements in pharmaceuticals and materials science. Its versatility and reactivity make it an invaluable tool in modern chemical research.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C7H4Cl2O2
Assay 99%
Appearance white powder
CAS No.  7693-45-0
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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