4-Hydroxycoumarin CAS:1076-38-6
4-Hydroxycoumarin (C9H6O3) is a significant member of the coumarin class of compounds, which are characterized by their fused benzene and α-pyrone rings. The presence of a hydroxyl group at the fourth carbon enhances its reactivity and biological activity, making it an important compound in medicinal chemistry and organic synthesis. One of the most notable applications of 4-hydroxycoumarin is its role as a precursor in the synthesis of anticoagulant medications. Warfarin, one of the most widely prescribed blood thinners, is derived from this compound. The anticoagulant properties stem from its ability to inhibit vitamin K epoxide reductase, an enzyme crucial for the synthesis of clotting factors in the liver. This mechanism helps prevent blood clot formation, making it essential in managing conditions such as deep vein thrombosis and atrial fibrillation. Beyond its pharmaceutical applications, 4-hydroxycoumarin exhibits a range of biological activities, including antifungal, antibacterial, and anti-inflammatory effects. These properties open doors for potential therapeutic applications in treating infections and inflammatory diseases. Research into its mechanisms of action continues to reveal insights that could lead to the development of new drugs. In synthetic organic chemistry, 4-hydroxycoumarin serves as a versatile building block for the creation of complex molecules. Its ability to undergo various transformations, such as esterification and acylation, allows chemists to modify its structure for specific applications. However, it is crucial to handle 4-hydroxycoumarin with care due to possible toxicity and irritative effects. Adhering to appropriate safety guidelines during laboratory and industrial use is essential. In conclusion, 4-hydroxycoumarin is a critical compound with far-reaching implications in medicine and chemistry, demonstrating the importance of continued research in this area.
Composition | C9H6O3 |
Assay | 99% |
Appearance | white powder |
CAS No. | 1076-38-6 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |