The Belt and Road: Cooperation, Harmony and Win-Win
products

Products

4-METHOXYPHENYL CHLOROFORMATE CAS:7693-41-6

4-Methoxyphenyl chloroformate is an organic compound featuring a 4-methoxy substituted aromatic ring linked to a chloroformate functional group. This compound functions as a versatile acylating agent in organic synthesis, facilitating the formation of esters and carbamates by reacting with nucleophiles such as alcohols and amines. The methoxy substituent enhances the electrophilic character of the chloroformate carbon, improving reactivity during acylation reactions. Its applications span across pharmaceutical development, agrochemicals, and materials science, where it contributes to the synthesis of biologically active compounds. Understanding its properties and reactivity patterns is essential for chemists using this compound effectively.


Product Detail

Product Tags

Application and Effect:

4-Methoxyphenyl chloroformate (C9H9ClO3) is a valuable reagent in the field of organic chemistry, particularly known for its role in acylation reactions. The presence of the methoxy group on the aromatic ring increases the electron density at the ortho and para positions, enhancing the electrophilicity of the adjacent chloroformate carbon. This property makes 4-methoxyphenyl chloroformate an effective acylating agent, allowing for rapid and efficient nucleophilic substitution with various nucleophiles, such as alcohols and amines. One of the primary uses of 4-methoxyphenyl chloroformate is in the synthesis of esters. When reacted with alcohols, the compound can yield corresponding esters that often exhibit desirable properties, making them suitable for use in fragrances, cosmetics, and food flavoring. Additionally, when 4-methoxyphenyl chloroformate reacts with amines, it produces carbamates, which are crucial intermediates in the synthesis of pharmaceuticals and agrochemicals. In pharmaceutical research, the ability to introduce the 4-methoxyphenyl moiety into target molecules can significantly enhance their biological activity, selectivity, and solubility. The methoxy group not only modifies the physicochemical properties of the compounds but can also influence their interaction with biological targets. Moreover, 4-methoxyphenyl chloroformate is used as a protecting group for alcohols and amines in complex synthetic routes. It allows for selective deprotection under mild conditions, providing chemists with greater control over reaction pathways and the overall synthesis of multi-functionalized compounds. While utilizing 4-methoxyphenyl chloroformate, careful handling is necessary due to its irritant nature and potential toxicity. Adhering to safety protocols, including working in fume hoods and wearing appropriate protective equipment, is essential. In summary, 4-methoxyphenyl chloroformate is a crucial reagent in organic synthesis, enabling the development of complex molecules in pharmaceuticals, agrochemicals, and materials science, thereby playing a significant role in modern chemical research.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C8H7ClO3
Assay 99%
Appearance white powder
CAS No.  7693-41-6
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


  • Previous:
  • Next:

  • Write your message here and send it to us