4-N-BUTOXYPHENYLACETIC ACID CAS:1658-42-0

4-N-Butoxyphenylacetic acid (C12H16O3) is an aromatic carboxylic acid that falls under the category of substituted phenylacetic acids. Its molecular structure consists of a phenyl ring with a butoxy substituent at the para position and an acetic acid functional group. The introduction of the butoxy group enhances the lipophilicity of the molecule, which plays a crucial role in its pharmacokinetic properties, including absorption, distribution, metabolism, and excretion. This compound has attracted attention within the pharmaceutical industry primarily due to its potential as an anti-inflammatory and analgesic agent. Research indicates that structurally similar compounds exhibit significant activity against various inflammatory pathways, suggesting that 4-N-butoxyphenylacetic acid may also exert similar effects. By modulating the production of prostaglandins and other mediators involved in inflammation, this compound could offer therapeutic benefits for conditions such as arthritis and other pain-related disorders. The synthesis of 4-N-butoxyphenylacetic acid usually involves the reaction of 4-nitrophenol with butyl bromide followed by reduction and subsequent acylation with acetic anhydride or acetic acid. This synthetic route is significant for producing the compound in sufficient quantities for both research and commercial applications. Furthermore, ongoing studies are exploring the safety profile and potential toxicity of 4-N-butoxyphenylacetic acid. Understanding these aspects is essential for evaluating its suitability as a therapeutic agent. Overall, the promising biological activities associated with 4-N-butoxyphenylacetic acid underscore its importance in drug discovery and development. Continued research efforts aim to optimize its formulation and evaluate its efficacy in clinical settings, paving the way for new treatment options in managing pain and inflammation.