4-PHENOXYPHENYLBORONIC ACID CAS:51067-38-0

In organic chemistry, boronic acids like 4-phenoxyphenylboronic acid are known for their ability to engage in Suzuki-Miyaura coupling reactions. This is a type of palladium-catalyzed cross-coupling reaction that allows for the formation of new C-C bonds between aryl halides and boronic acids. The reaction is particularly useful for the construction of complex organic structures and is widely used in the synthesis of pharmaceuticals and materials science. 4-Phenoxyphenylboronic acid itself is a white to pale yellow solid that is soluble in organic solvents such as dichloromethane and tetrahydrofuran. Its solubility in these solvents makes it convenient for use in organic reactions and for purification procedures. The presence of the phenoxy group in the molecule increases its polarity, which can influence its reactivity and solubility. The phenoxy group can act as a donor in hydrogen bonding, which can be important for its interactions with other molecules. In summary, 4-Phenoxyphenylboronic acid is a valuable reagent in organic chemistry, particularly for its role in Suzuki-Miyaura coupling reactions. Its unique structure and reactivity make it a useful tool for the synthesis of complex organic compounds.