5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde CAS:881677-11-8
5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde is synthesized through intricate organic reactions utilizing commercially available starting materials. The synthesis involves precise manipulation of reaction conditions to achieve regioselective cyclization and subsequent introduction of the fluorophenyl and pyridin-3-ylsulfonyl groups. This ensures the synthesis of a compound with desired structural features and potential biological activities. Synthetic Routes The synthesis begins with the formation of the pyrrole ring system through controlled cyclization reactions, aiming for regioselectivity to position the substituents correctly. Subsequent steps involve functionalization of the pyrrole core with a 2-fluorophenyl group and introduction of the pyridin-3-ylsulfonyl moiety, requiring specialized reagents and reaction conditions to avoid side reactions and ensure high yield and purity. Chemical Properties and Reactivity 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde exhibits distinct chemical properties arising from its molecular structure. The presence of the pyrrole, fluorophenyl, and pyridin-3-ylsulfonyl groups imparts unique reactivity, offering opportunities for diverse organic transformations and potential interactions with biological targets. Understanding its chemical behavior is crucial for exploiting its therapeutic potential and designing novel molecules for medicinal applications. Biological and Pharmacological Significance The compound holds promise for various biological activities that could be explored for pharmaceutical purposes. Its structural complexity suggests roles as a molecular scaffold for designing compounds targeting specific biological receptors or enzymes, with potential applications in drug discovery and development. Elucidating its interactions with biological systems is essential for evaluating its pharmacological profile and therapeutic potential. Applications in Medicinal Chemistry 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde serves as a valuable intermediate in medicinal chemistry for synthesizing analogs with tailored properties. Structural modifications around the pyrrole, fluorophenyl, and pyridin-3-ylsulfonyl groups can significantly influence factors such as bioactivity, solubility, and metabolic stability, crucial for optimizing drug candidates. Its versatility makes it suitable for designing compounds aimed at addressing diverse therapeutic targets and diseases. Conclusion 5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbaldehyde represents a significant compound in the fields of medicinal chemistry and organic synthesis, characterized by its intricate molecular structure and potential biological activities. Its synthesis pathway and chemical properties provide a platform for further exploration in pharmaceutical research, highlighting its role in advancing drug discovery efforts. Continued investigation into its reactivity and interactions with biological systems is expected to unveil new therapeutic opportunities, underscoring its relevance in scientific and pharmaceutical innovations.
Composition | C16H11FN2O3S |
Assay | 99% |
Appearance | white powder |
CAS No. | 881677-11-8 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |