5-Amino-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-8-carboxylic acid CAS:2060031-16-3

This multi-functional building block enables efficient synthesis of pharmacophores and advanced materials. Reactions at the amine and carboxylic acid install new groups to develop analog libraries. Deprotection of the Boc group permits derivatization of the aromatic ring. Additionally, the rigid, electron-rich structure supports transition metal-catalyzed cross-coupling and cycloaddition transformations. These generate heterocyclic fragments valuable for drug discovery. This molecule is also suitable as a monomer for producing optically active polymers with tailored properties. The various reactive sites thus render this an important synthon for pharmaceuticals and functional materials development.