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5-Chloro-2-fluoropyridin-3-ylboronic acid CAS:937595-70-5

5-Chloro-2-fluoropyridin-3-ylboronic acid is a boron-containing compound characterized by a pyridine ring with chlorine and fluorine substituents at the fifth and second positions, respectively, along with a boronic acid functional group (-B(OH)₂) at the third position. Its molecular formula is C5H4ClFBN2O2. This compound is notable for its utility in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The presence of the boronic acid moiety allows for participation in cross-coupling reactions, making it an important building block for creating complex organic structures with diverse biological activities.

 


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Application and Effect:

5-Chloro-2-fluoropyridin-3-ylboronic acid serves as a versatile intermediate in organic synthesis, particularly in the fields of medicinal chemistry and materials science. Its unique structure combines the reactivity of both halogen and boronic acid functionalities, allowing for a variety of synthetic applications. One of the primary uses of this compound is in the synthesis of pharmaceutical agents. The boronic acid group can participate in Suzuki-Miyaura cross-coupling reactions, facilitating the formation of carbon-carbon bonds between aryl or vinyl groups. This reaction has become a cornerstone in pharmaceutical chemistry, enabling the construction of complex molecular architectures that are essential for developing new therapeutics. Researchers have used 5-chloro-2-fluoropyridin-3-ylboronic acid to synthesize potential drug candidates targeting various diseases, including cancer and infectious diseases. In addition to its pharmaceutical applications, 5-chloro-2-fluoropyridin-3-ylboronic acid is also significant in agrochemical synthesis. The ability to modify and introduce different substituents through coupling reactions enhances the design of herbicides and pesticides with improved efficacy and selectivity for agricultural use. This is crucial for developing sustainable crop protection strategies amid growing global food demands. Moreover, this compound is gaining attention in materials science, particularly for the synthesis of functionalized polymers and advanced materials. The boronic acid group can act as a reactive site for polymerization processes or modifications, leading to materials with tailored properties for specific applications, such as sensors, catalysts, and drug delivery systems. In summary, 5-chloro-2-fluoropyridin-3-ylboronic acid is a valuable compound that plays a pivotal role in organic synthesis across multiple domains, including pharmaceuticals, agrochemicals, and materials science. Ongoing research continues to explore its potential, revealing new pathways for innovation in chemical synthesis and application.

Product Sample:

L-Arginine1
L-Arginine2

Product Packing:

L-Arginin3

Additional Information:

Composition C5H4ClFBN2O2
Assay 99%
Appearance white powder
CAS No.  937595-70-5
Packing Small and bulk
Shelf Life 2 years
Storage Store in cool and dry area
Certification ISO.

 


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