5′-O-Tritylthymidine CAS:7791-71-1 Manufacturer Price

5′-O-Tritylthymidine is a derivative of thymidine, which is a nucleoside composed of the pyrimidine base thymine linked to a deoxyribose sugar. The trityl group is a protecting group commonly used in organic synthesis to temporarily mask a reactive functional group. In the case of 5′-O-Tritylthymidine, the trityl group is attached to the 5′ hydroxyl group of the deoxyribose sugar of thymidine. This modification is often employed in the synthesis and modification of nucleic acids, particularly in the context of solid-phase DNA synthesis. The trityl group serves to protect the 5′ hydroxyl group during chemical reactions and can be selectively removed under mild conditions to generate the free hydroxyl group for subsequent manipulations. This compound finds applications in the field of nucleic acid chemistry and oligonucleotide synthesis.