6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one hydrochloride CAS:571188-82-4

The compound features a pyrido[2,3-d]pyrimidine core, with a bromo group attached to the 6-position of the larger ring, introducing a strong electron-withdrawing effect that influences the molecule's reactivity. The cyclopentyl ring at the 8-position adds a degree of steric hindrance, while the 5-methyl and 7-oxo groups increase the compound's lipophilicity. The piperazine ring is connected to the pyridine ring via an amide linkage, providing a point of amination and potential for further functionalization. The tert-butyl ester group at the 1-position of the piperazine ring serves as a protecting group, preventing unwanted reactions at the amine site. The carboxylic acid functionality is present as a tert-butyl ester, which is a common protecting group for carboxylic acids, offering improved handling and stability. This ester can be easily converted to the corresponding carboxylic acid when needed. Overall, this compound is likely to be of interest in the fields of medicinal chemistry and organic synthesis due to its complex structure and the presence of various functional groups that offer potential for biological activity and synthetic utility.