6-Amidino-2-naphtol methanesulfonate CAS:82957-06-0

6-Amidino-2-naphthol methanesulfonate finds wide-ranging applications in numerous scientific and research areas. One notable application is its utilization as a chromogenic substrate for the detection of specific enzymes, particularly amidases and alkaline phosphatases. Its unique chemical properties make it an advantageous candidate for such enzyme assays. The compound undergoes a color change upon enzymatic hydrolysis, allowing for easy visual or spectrophotometric determination of enzyme activity levels. Furthermore, 6-Amidino-2-naphthol methanesulfonate is utilized in cell biology studies for the visualization of nucleic acids. It can be employed as a stain to detect DNA and RNA in cells or tissues. This characteristic makes it valuable in techniques like in situ hybridization and immunohistochemistry, aiding researchers in studying gene expression patterns and cellular localization. Moreover, this compound is also employed in medical research, specifically in studies related to blood clotting mechanisms. It acts as a potent inhibitor of tissue factor pathway inhibitor (TFPI), a key regulator in the coagulation cascade. By inhibiting TFPI, 6-Amidino-2-naphthol methanesulfonate allows for a better understanding of the intricacies of coagulation processes and may have therapeutic implications in the future. In addition, 6-Amidino-2-naphthol methanesulfonate finds application in analytical chemistry for the quantification of amino acids and peptides. It can be used as a derivatizing agent to improve the detection sensitivity of these biomolecules in various analytical techniques, including liquid chromatography. Overall, the versatile properties of 6-Amidino-2-naphthol methanesulfonate make it a valuable tool in enzyme assays, cell biology, medical research, and analytical chemistry. Its broad range of applications highlights its significance in advancing scientific knowledge and facilitating various experimental investigations.