6-benzylguanine CAS:19916-73-5

6-Benzylguanine serves diverse purposes across several scientific and medical domains due to its unique biochemical properties. In the field of biological research, it is utilized as a valuable tool for studying DNA repair mechanisms, protein-DNA interactions, and enzyme inhibition. As a specific inhibitor of the enzyme O6-alkylguanine-DNA alkyltransferase (AGT), it is employed to investigate the role of AGT in DNA damage repair pathways and its impact on cellular response to alkylating agents and chemotherapy drugs. This contributes to a deeper understanding of DNA repair processes and mechanisms of chemoresistance, offering insights into potential strategies for cancer therapy and personalized medicine. Furthermore, 6-Benzylguanine finds application in pharmaceutical research and drug development, where it is studied for its potential therapeutic applications in combination with alkylating agents and chemotherapeutic drugs. By targeting AGT, it may potentiate the effects of chemotherapeutic agents by inhibiting DNA repair processes in cancer cells, thereby enhancing the efficacy of chemotherapy and potentially overcoming resistance to certain anticancer treatments. Moreover, this compound may be utilized in the production of specialized reagents and tools used in molecular biology and biotechnology applications. Its use as a modulator of DNA repair and as a research tool in studies of gene expression, cell signaling, and cancer biology contributes to the advancement of research techniques and the understanding of disease mechanisms. Additionally, 6-Benzylguanine holds significance in academic and industrial research as a reference standard in analytical chemistry and in the investigation of nucleotide metabolism and DNA repair pathways. Its use in experimental assays and analytical methods contributes to the accurate characterization of biomolecular interactions, aiding in the elucidation of complex biological processes and signaling networks. Overall, the multifaceted utility of 6-Benzylguanine underscores its significance in advancing scientific knowledge, supporting pharmaceutical innovation, and facilitating progress in biomedical research, making it an essential tool in various applications within the life sciences and drug discovery.