6-((tert-butoxycarbonylamino)methyl)nicotinic acid CAS:170097-87-7
6-((tert-butoxycarbonylamino)methyl)nicotinic acid serves as a versatile building block across multiple industries, enabling the synthesis of compounds with significant applications: Medicinal Chemistry: This compound plays a pivotal role in medicinal chemistry, particularly in the development of novel pharmaceuticals targeting various therapeutic areas such as cardiovascular diseases, inflammation, and metabolic disorders. Its structural versatility allows for modifications crucial for optimizing pharmacological properties and enhancing drug efficacy. Peptide Conjugation: Chemists utilize 6-((tert-butoxycarbonylamino)methyl)nicotinic acid in peptide conjugation reactions, facilitating the attachment of bioactive peptides to small molecules or nanoparticles for targeted drug delivery and imaging applications. The tert-butoxycarbonyl-protected amino group provides stability during conjugation, ensuring efficient and selective coupling reactions. Prodrug Design: Researchers employ its structural motifs in designing prodrugs, which are inactive compounds that undergo enzymatic or chemical transformation in vivo to release active pharmaceutical agents. The presence of the tert-butoxycarbonyl group allows for controlled activation of the prodrug, improving drug delivery, bioavailability, and patient compliance. Chemical Biology: 6-((tert-butoxycarbonylamino)methyl)nicotinic acid serves as a valuable tool in chemical biology research for labeling and imaging biomolecules such as proteins and nucleic acids. Its ability to undergo bioorthogonal reactions enables specific and selective labeling of cellular targets, facilitating studies on biological processes and disease mechanisms. In summary, 6-((tert-butoxycarbonylamino)methyl)nicotinic acid is a versatile compound with extensive applications in medicinal chemistry, peptide conjugation, prodrug design, and chemical biology. Its unique structural properties and synthetic versatility contribute to advancements in drug discovery and biological research.
Composition | C12H16N2O4 |
Assay | 99% |
Appearance | white powder |
CAS No. | 170097-87-7 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |