Angiotensin Ⅱ CAS:4474-91-3

Angiotensin II is involved in various physiological processes, including regulation of blood pressure, fluid and electrolyte balance, and systemic vascular resistance. It plays a crucial role in the maintenance of blood pressure and kidney function. Dysregulation of the renin-angiotensin system can lead to hypertension, heart failure, and kidney disease. Medications targeting the renin-angiotensin system, such as ACE inhibitors and angiotensin receptor blockers, are commonly used to treat conditions like hypertension, heart failure, and diabetic kidney disease by modulating the effects of Angiotensin II. In addition, Angiotensin II is also used clinically as a vasoactive drug in certain situations such as septic shock, where its vasoconstrictive effects help to maintain blood pressure and organ perfusion. It can be administered in intensive care settings under careful monitoring to support blood pressure in patients with severe hypotension. However, due to its potent vasoconstrictive properties, its use requires close monitoring and should only be administered by healthcare professionals experienced in its use.