Aprotinin CAS:9087-70-1 Manufacturer Price

Aprotinin is a protease inhibitor that has been used in medical procedures to reduce bleeding and blood transfusion requirements. Its main application is in cardiovascular surgeries, such as coronary artery bypass grafting (CABG), valve replacement, and other complex surgeries involving the heart and blood vessels.

The effect of aprotinin is primarily based on its ability to inhibit the activity of proteolytic enzymes, specifically trypsin, chymotrypsin, and plasmin. These enzymes are involved in the breakdown of blood clots and the degradation of fibrin, a protein that helps in the formation of clots.

By inhibiting these enzymes, aprotinin helps maintain the stability of formed blood clots, reducing the risk of excessive bleeding during and after surgery. This can lead to a decrease in the need for blood transfusions and surgical revisions, potentially improving patient outcomes.