azathioprine usp CAS:446-86-6

The primary use of Azathioprine USP is in organ transplantation to suppress the immune system's response and prevent rejection of the transplanted organ. By inhibiting the proliferation of immune cells, particularly T lymphocytes, Azathioprine helps maintain the body's acceptance of the new organ and improves transplant success rates.

In autoimmune conditions like rheumatoid arthritis and inflammatory bowel disease, Azathioprine is used to reduce inflammation and control the overactive immune response that leads to tissue damage. It modulates the immune system's activity, thereby alleviating symptoms and slowing down disease progression in patients with these chronic inflammatory conditions.

Additionally, Azathioprine USP is sometimes prescribed off-label for other autoimmune disorders, such as systemic lupus erythematosus and dermatomyositis, where immune system dysfunction plays a significant role in disease pathogenesis. Its immunosuppressive properties make it a valuable treatment option for managing various autoimmune conditions and improving patients' quality of life by reducing symptoms and disease activity.