Benzo[b]thiophen-2(3H)-one CAS:496-31-1
The synthesis of Benzo[b]thiophen-2(3H)-one typically involves synthetic routes utilizing readily available starting materials. Common methods include the cyclization of o-mercapto phenyl ketones under oxidative conditions to yield the desired benzo[b]thiophen-2(3H)-one scaffold. Analytical techniques such as NMR, IR, and mass spectrometry are employed to confirm the compound's structure and purity. Molecularly, Benzo[b]thiophen-2(3H)-one consists of a benzene ring fused to a thiophene ring, with a ketone functional group at the 2-position of the thiophene ring. This structural motif offers opportunities for diverse chemical modifications and interactions with biological targets. Pharmacological Significance and Potential Applications The structural versatility of Benzo[b]thiophen-2(3H)-one makes it a promising candidate for pharmaceutical research. Thiophene derivatives have been investigated for a range of pharmacological activities, including as antimicrobial, anti-inflammatory, and anticancer agents. The presence of the ketone group adds chemical diversity and potential reactivity, allowing for the design of analogs with improved pharmacokinetic properties and biological activities. Benzo[b]thiophen-2(3H)-one may serve as a scaffold for the development of novel therapeutic agents targeting various disease indications, including infectious diseases, inflammatory disorders, and cancer. Its unique structure offers opportunities for structure-activity relationship studies to optimize potency, selectivity, and safety profiles. In conclusion, Benzo[b]thiophen-2(3H)-one presents an intriguing molecular scaffold with significant pharmaceutical implications. Further research into its synthesis, pharmacology, and medicinal chemistry is essential to fully exploit its therapeutic potential and applications in drug discovery and development.
Composition | C8H6OS |
Assay | 99% |
Appearance | white powder |
CAS No. | 496-31-1 |
Packing | Small and bulk |
Shelf Life | 2 years |
Storage | Store in cool and dry area |
Certification | ISO. |