Boc-Trp-OSu CAS:3392-11-8

Boc-Trp-OSu is instrumental in bioconjugation chemistry, particularly in the functionalization of peptides and proteins for targeted applications. As an NHS ester derivative, it facilitates the covalent coupling of the Boc-protected tryptophan moiety with primary amines present in amino acids, peptides, or proteins. This selective conjugation allows for the precise modification of specific amino acid residues within a peptide sequence or the N-terminus of a protein, enabling the introduction of functional groups or labels for various purposes. Researchers and biochemists utilize Boc-Trp-OSu in the development of peptide conjugates for applications such as targeted drug delivery, immunoassays, and biomaterial functionalization. By coupling Boc-Trp-OSu-modified peptides to targeting molecules or surfaces, they can create bioactive constructs capable of selectively interacting with cellular receptors, antigens, or biological matrices. Additionally, Boc-Trp-OSu finds application in the preparation of peptide-protein conjugates for generating antibody-drug conjugates (ADCs) and protein labeling for imaging and diagnostic assays. The versatility of Boc-Trp-OSu makes it an indispensable tool in diverse fields such as chemical biology, biotechnology, and pharmaceutical sciences. Its compatibility with bioconjugation protocols, high reactivity, and selectivity contribute to its widespread use in academic and industrial settings. Whether applied in basic research or the development of advanced therapeutics, Boc-Trp-OSu enables the creation of tailored peptide conjugates that are pivotal in advancing targeted therapies and molecular diagnostics.