Calpain Inhibitor IV CAS:133407-82-6

Calpain Inhibitor IV is a type of drug that specifically targets and inhibits the activity of the enzyme calpain. Calpain is a calcium-dependent protease enzyme that plays a role in various cellular processes, including cell signaling, apoptosis, and cytoskeletal remodeling.

By inhibiting calpain, Calpain Inhibitor IV helps prevent the excessive and uncontrolled activation of this enzyme, which can lead to cellular damage and dysfunction. This inhibition can be beneficial in conditions where calpain overactivity is implicated, such as neurodegenerative disorders like Alzheimer’s and Parkinson’s diseases, ischemic injury, or muscle degeneration conditions.

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Application and Effect

Neuroprotection: Calpain has been implicated in neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. By inhibiting calpain activity, Calpain Inhibitor IV may offer neuroprotective effects and help mitigate neuronal damage.

Muscular disorders: Uncontrolled calpain activity has been associated with muscle degradation and muscular disorders such as muscular dystrophy. Calpain inhibitors could potentially help in reducing muscle damage and improving muscle function.

Cancer research: Calpain enzymes can contribute to tumor invasion and metastasis. Therefore, calpain inhibitors, including Calpain Inhibitor IV, might be used in cancer research to examine their effects on tumor growth, invasion, and metastasis.

Inflammation: Calpain enzymes have been implicated in inflammation and inflammatory diseases. Calpain inhibitors may help alleviate inflammation by suppressing calpain-mediated immune responses.

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Additional Information:

Composition	C26H41N3O5
Assay	99%
Appearance	Light yellow powder
CAS No.	133407-82-6
Packing	Small and bulk
Shelf Life	2 years
Storage	Store in cool and dry area
Certification	ISO.